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RECENTS

The Most Effective Way to Consume Cannabis: Cannabis Extracts and Bio-Availability

Updated: May 10, 2023

In an effort to clarify the most effective method of cannabis consumption, and therefore the least effective methods, we dove into several research journals along with a long list of cannabis websites and publications. While we can narrow down the scope of findings and information, this is yet another project that makes one thing absolutely clear: WE CAN NOT TRUST ANYONE, ANYWHERE, IN THIS INDUSTRY FOR ANY INFORMATION.




After perusing fifteen to twenty online articles, our research once again came to a quick close, realizing there is far more bad than good. Our poignantly focused topic (unassumingly heavily written upon) is yet another example highlighting the industry's incompetent willingness to make unqualified statements, even when they contradict common sense. Criticism is still highly lacking in this partially cloaked continuation of the over-exaggerated and over-generalized, for-profit, "medicinal" charade.


Hash Rosin Cannabis in big glass jar, just before the hash rosin badder whip, or #baddertech technique is applied.
This is what a quality cannabis flower looks like in 2022-2023

Bio-Availability

Is the ability of a drug to be absorbed into the bloodstream. Coming from other areas of intoxication, bio-availability played a key role in researching the synthetic pharmacopoeia Millennials much like myself, learned to skillfully navigate. An understanding of pharmaceutical's bio-availability for instance, allowed us to measure an equivalent dose of one opioid to another. In cannabis the term rarely applies, but a single lesson on the various methods of consumption and the averages we do know, can help focus attention to effective products and especially to the most effective routes of administration. Like the butt-hole.


Route of Consumption

The metabolism of cannabis is determined by the route of consumption. This played a huge part in safely using opioids with drastically different bio-availabilities depending upon the route of consumption. Readers can imagine why mainlining is preferred (and read why later). While many articles and publications go into the absorbed effects of THC alone in transdermals, patches, topicals, etc., my interest lies in the various methods of inhalation and their obvious differences, despite article after article with incorrect information that doesn't distinguish the two.


MISINFORMATION CANNABIS PLANET

Finding numerous publications stating that combustion smoke consumption is equivalent to the bio-availability of vaporized THC, this is purely and obviously false. It only requires a momentary connection between dabbing ice water hash and the temperatures when terpenes and cannabinoids vaporize, to see the error in logic. Furthermore, we know the temperature when THC is destroyed and converted to CBN, that happens long before actual combustion smoke ever occurs. Common sense in mind, here are several examples from leading publications and top search results:


Leafly says: "However, the bioavailability of THC is still limited when consumed orally, averaging only 4-12%. When smoked or vaped, the bioavailability of THC leaps to an average of 30%," combining combustion smoked cannabis as equal to vaporized cannabis. Again, this is absurd.


"The bio-availability of inhaled THC is 10% to 35%. After THC is absorbed, it travels to the liver where most of it is eliminated or metabolized to 11-OH-THC or 11-COOH-THC. The remaining THC and its metabolites enter the circulation. Across all users, light and heavy, the bioavailability for inhaled THC is between 10% and 35%".


"By definition, drugs administered intravenously have a bioavailability of 100%" (there you go). "Smoking and vaping are one of the more efficient methods in terms of bioavailability. One study found that smoked THC has an average bioavailability of 30% while, in contrast, orally ingested THC ranges from 4% to 12%. The results for CBD are similar when comparing smoking to oral ingestion." -Encore Labs